The Liu lab is interested in centrosome and cilium, whose defects cause severe human diseases such as cancer, microcephaly and ciliopathies. Because centrosome and cilium are tiny cellular organelles, conventional microscopy fails to reveal their detailed architecture. In LIU lab, we leverage super-resolution fluorescence microscopy to study centrosome and cilium and diagnose human diseases caused by their defects. By applying state-of-art techniques, we focus on mechanistic and translational studies that directly benefit patients.